Medical School

Division of Blood and Marrow Transplantation

Department of Pediatrics

John Wagner, MD

MEDPEDS2 - Image - 180x222 - John Wagner Jr.

Academic Title


Clinical Title

Pediatric Hematologist Oncologist


Medical School
Jefferson Medical College, Philadelphia, Pennsylvania
Pediatrics, Duke University Medical Center, Durham, NC
Hematology-Oncology, Johns Hopkins Hospital, Baltimore, MD

Contact Info


(612) 626-2961

(612) 626-4074

Office Address

Pediatric BMT
660 MCRB
425 East River Rd
Minneapolis, MN 55455

Mailing Address

Pediatrics BMT
MMC 366 Mayo
8366A (Campus Delivery Code)
420 Delaware St SE
Minneapolis, MN 55455

Bio Statement

Dr. Wagner is a professor of pediatrics, Director of the Division Blood and Marrow Transplantation, and Co-Director of the Center for Translational Medicine at the University of Minnesota. He currently holds two endowed chairs – Hageboeck/Children’s Cancer Research Fund Chair in Pediatric Cancer Research, and the University of Minnesota McKnight Presidential Chair in Hematology and Oncology. Dr. Wagner is internationally recognized as an expert in the field of stem cells and umbilical cord blood transplantation.

He received his M.D. degree at Jefferson Medical College in 1981, completed his internship and residency in Pediatrics at Duke University School of Medicine in 1984 and postdoctoral fellowship in Hematology-Oncology at The Johns Hopkins School of Medicine in 1987, where he remained until joining the faculty at the University of Minnesota in 1991. He is board certified in pediatrics and pediatric hematology/oncology.

Dr. Wagner’s research has focused on the development of new treatment approaches for life-threatening diseases for which conventional treatments are unsatisfactory using molecular and cellular therapies. While historically, most of his work is in the setting of leukemia and bone marrow transplantation, new possibilities now exist allowing us to consider moving outside this area – such as the area of skin diseases, cardiovascular diseases, diabetes, and neurological diseases.

He has authored 237 research papers and book chapters, and is a member of numerous professional societies.

Research Interests

  1. Umbilical Cord Blood Transplantation in Children and Adults
    • Ex vivo expansion of hematopoietic stem cells
    • Double unit transplantation
    • Non-myeloablative preparative therapies
    • Co-infusion of T-regulatory cells
    • Graft vs. Leukemia Effector Therapies
  2. Fanconi anemia
    • Novel preparative therapies
    • Gene therapy - multipotent adult stem cell
    • Phenotype-genotype correlations (collaboration with Rockefeller University)
    • Pathophysiology
  3. Multipotent Adult Stem Cells (MAPC) in tissue repair
    • Translational development/large scale manufacture of MAPC
    • Evaluation of MAPC therapeutic potential in congenital and acquired disorders

  • 1981 Dean Marie Baines Award for Excellence in Pediatrics, Jefferson Medical College
  • 1981 Magna Cum Laude, Jefferson Medical College
  • 1990-1993 Recipient, American Cancer Society Clinical Oncology Career Development Award
  • 2000 Elected to the American Society of Clinical Investigation
  • 2001 Tenth Clinical Scholar Award, University of Minnesota Medical School and Fairview-University Medical Center
  • 2002 Recognition of Excellence, Academic Health Center, University of Minnesota
  • 2002 Pioneer Award for Therapeutic Advancement Fanconi Anemia Research Fund
  • 2003 1st Recipient of the Brady Kohn Foundation Award
  • 2004 Invited speaker on the Clinical Application of Stem Cells at the United Nations
  • 2005 Testified before theUnited States Senate on the effectiveness of umbilical cord blood prior to passage of the Stem Cell Act of 2005
  • 2006 Elected to Association of American Physicians
  • 2009-2010 Best Doctors in America

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  • Last modified on March 21, 2013