| Study Number | Title | Disease |
| 1941 | Bone Marrow Transplantation Versus Prolonged Intensive Chemotherapy for Children with Acute Lymphoblastic Leukemia After an Initial Bone Marrow Relapse | |
| 1951 | Extramedullary Relapse and Occult Bone Marrow Involvement in Childhood Acute Lyphoblastic Leukemia | |
| 1952 | Randomized Comparisons of Oral MP vs. Oral TG and IT MTX vs. ITT for Standard Risk Acute Lyphoblastic Leukemia | |
| 1961 | Treatment of Acute Lymphoblastic with Unfavorable Features | |
| 1962 | A randomized Comparison of PEG and Native E. Coli Asparaginases in the Standard Arm of CCG-1952 for Standard Risk Acute Lymphoblastic Leukemia | |
| 2891 | Acute Non-Lymphocytic Leukemia (ANLL) and Myelodysplastic Syndrome (MDS) Down Syndrome Patients Only | ANLL/MDS |
| 2951 | Acute Myeloid Leukemia Salvage Therapy for Patients in First Relapse or Who Fail to Achieve an Initial Remission or Who Develop Acute Myeloid Leukemia as a Second Malignant Neoplasm | AML/MDS |
| 2961 | Study in Children with Untreated Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS) | AML/MDS |
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| 5941 | Phase II Pilot Study For The Treatment Of Newly Diagnosed Disseminated Lymphoblastic Lymphoma And T-Large Cell Lymphoma | |
| 5942 | A Comprehensive Study of Clinically Staged Pediatric Hodgkin's Disease: Chemotherapy for all Patients; Supplementary Low Dose Involved Field Radiation for Selected Patients | Hodgkin's |
| 5961 | FAB LMB 96 - Treatment of Mature B-Cell Lymphoma/Leukemia | Hodgkin's |
| Protocol |
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| 0952 Limited | Phase I Study of Topotecan and Involved Field Radiation for Intrinsic Pontine Glioma of Childhood | Intrinsic Pontine Glioma |
| 9933 | Phase II Study of High Dose Pre-Irradiation Chemotherapy (Vyvlophosphamide/VP-16/Mesna or Ifosfamide/VP-16/Mesna or Carboplatin/VP-16) in Children with Newly-Diagnosed High-Grade Astrocytoma | Astrocytoma |
| 9942 | Ohase II Trial of Pre-Irradiation Vincristine, Cisplatin, Cyclophosphamide and Etoposide Chemotherapy for Children Aged 3 to 21 Years with Newly-Diagnosed Intracranial Ependymoma and Radiologic Evidence of Postoperative Residual Tumor | Ependymoma |
| 9952 | Phase II Study of Chemotherapy for Progressive Low Grade Astrocytoma in Children Less Than Ten Years Old | Astrocytoma |
| A9961 | A Prospective Randomized Study of Craniospinal Radiotherapy Followed by One of Two Adjuvant Chemotherapy Regimens (CCNU, CDDP, VCR or CPM,CDDP,CDR) in Children with Newly-Diagnosed Average-Risk Medulloblastoma | Medulloblastoma |
| 99703 Groupwide | Ap Pilot Study of Inensive Chemotherapy with Peripheral Stem Cell Support for Infants with Malignant Brain Tumors |
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| 3951 Limited | Phase I Pilot Study of High Dose Chemotherapy with Peripheral Blood Stem Cell Infusions in Advanced Stage Neuroblastoma |
| A3961 | Treatment for Infants and Children with Intermediate Risk Neuroblastoma |
| BSO | A Pilot Study of Buthionine Sulfoximine (BSO) in Combination with Melphalan for High Risk Neuroblastoma Patients |
| P9641 | Primary Surgical Theapy for Biologically Defined Low-Risk Neuroblastoma |
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| 7942 | A Randomized Evaluation of Intensified Vincristine, Doxorubicin, Cyclophosphamide, Ifosfamide, and Etoposide in the Treatment of Newly-Diagnosed Ewing's Sarcoma or PNET of Bone or Soft Tissue | Ewing's Sarcoma |
| 7943 | A Phase II Window of Topotecan in Children with Newly Diagnosed Metastatic Osteosarcoma | Osteosarcoma |
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| 8961 | Chemoembolization for the Treatment of Children with Unresected Non-Metastatic Hepatocellular Carcinoma or Chemotherapy Resistant Unresected Non-Metastatic Primary Liver Tumors |
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| 4941 | National Wilms' Tumor Study-V, Therapeutic Trial and Biology Study |
| 4942 | National Wilms' Tumor Study-V, Treatment of Relapsed Patients |
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Study
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| 6921 | Phase II Pilot Study for the Treatment of Patients with Rhabdomyosarcoma and Other Soft Tussue Sarcomas with Metastatic Disease at Diagnosis |
| D9501 Phase II |
Topotecan and Cyclophosphamide, Followed by Multimodal, Multiagent Therapy for Children and Adolescents with Newly Diagnosed Stage IV/Clinical Group IV Rhabdomyosarcoma, an IRS-V Pilot Study |
| D9502 | IRS-V: A pilot Study of Vincristine (VCR), Actinomycin-D (AMD), and Escalating Dose Cyclophosphamide (CTX) Therapy for Children with Localized Rhabdomyosarcoma at Increases Risk or Relapse and Metastatic Rhabdomyosarcoma with a Parameningeal Primary Site |
| D9602 | Actinomycin D and Vincristine with or without Radiation Therapy, for Newly Diagnosed Patients with Low-Risk Rhabdomyosarcoma or Undifferentiated Sarcoma: IRS-V Protocol |
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| 0903 Limited | Phase I Study of Taxol in Refractory Leukemia in Children |
| 0923 Groupwide | Phase II Trial of Carboxypeptidase-G2 for the Management of Patients with Intrathecal Methotrexate Overdose |
| 0933 Limited | Phase I Study of Continuous Infusion Ara-C in Children with Refractory ALL, AML and NHL with Marrow Involvement |
| 0935A Limited | Phase I Study of Chimeric Human/Murine Anti-GD2 Monoclonal Antibody with GM-CSF in Children with Neuroblastoma and Other GD2 Positive Malignancies Immediately Post Autologous BMT or PBSC Rescue |
| 0937 Limited | Phase I Trial of ZD1694 (Tomudex) an Inhibitor of Thymidylate Synthase inm Pediatric Patients with Advanced Neoplastic Disease |
| 0943 Limited | Phase I Study of C1-958 in Pediatric and Adolescent Patients with Relapsed Solid Tumors |
| 0952 Limited | Phase I Study of Topotecan and Involved Field Radiation Therapy for Intrinsic Pontine Glioma of Children |
| 0954 Limited | Phase I Study of Gemcitabine in Solid Tumors |
| 0955 Limited | Phase I Study of Gemcitabine in Children with Relapsed or Refractory Leukemia and Non-Hodgkin's Lymphoma |
| 0961 Intergroup | Phase II Trial of All-trans-Retinoic Acid in Combination with Interferon-alpha2a in Children with Recurrent Neuroblastoma or Wilms' Tumor |
| 0962 Groupwide | Phase II Study of Docataxel in Children with Recurrent Solid Tumors |
| 09705 Groupwide | Phase II Study of Navelbine (Vinorelbine) in Children with Recurrent or Refractory Malignancies |
| 09709 Limited | Phase I Study of Fenretinide in CHildren with High Risk Solid Tumors |
| 09717 | Phase I Study of Thrombopoietin (rhtpo) plus G-CSF following Ifosfamide, Carboplatin, Etoposide (I.C.E.) in Children with Recurrent or Refractory Solid Tumors |
| A09701 Groupwide | A Phase II Study of Temodal (Temozolomide) in Children and Adolescents with Recurrent Central Nervous System Tumors |
| P9462 Intergroup | Phase II Randomized Treatment of Refractory Neuroblastoma with Topotecan Regimens |
4941L
B003
Diagnostic and Prognostic Studies in Neuroblastoma
B24
Molecular Analysis of Preleukemic and Leukemic Marrow from Patients with Monosomy 7 and 7q-
B904
IRS Laboratory Evaluation of Tumor Tissue
B942
Detection of Minimal Residual Disease in Children Receiving Therapy for AML or MDS (Companion to CCG 2891/2941)
B944
Biology Studies in Childhood Hodgkin's and Non-Hodgkin's Lymphoma (Companion to CCG-5941/5942/5961)
B945
The Genetic Epidemiology of 11q23 Leukemia in the Young (Companion to CCG-2861/2961/1953)
B947
A Groupwide Protocol for Collecting and Banking Tumor Specimens
B951
Pharmacological Studies of L-Asparaginase in Pediatric Patients with ALL (Companion to CCG-1941)
B9511
Minimal Residual Disease Detection in High Risk Ewing's Sarcoma and PNET of Bone (Companion to CCG-7951)
B954
Opsoclonus-Myoclonus-Ataxia Syndrome, Neuroblastoma and the Presence of Anti-Neuronal Antibodies
B955
Environmental Exposures and ras Mutations in Acute Leukemia
B957
Genetic Etiology of Acute Leukemia in Down Syndrome
B958
Minimal Residual Disease in Relapsed Acute Lymphocytic Leukemia (Companion to CCG-1941/1951)
B961
Prognostic Significance of KI-67 Proliferative Index Utilizing the MIB-1 Antibody in Low Grade Gliomas in Young Children (Companion to CCG-9952)
B968
Intracellular RBC Thiopurine Pharmacokinetics in ALL Patients Receiving Oral 6MP vs Oral 6TG (Companion to CCG-1952)
B971
Molecular Biology of Pediatric Brain Tumors (Companion to CCG-9921/9931/A9961)
B972
Immune Status and Activation in Children Participating in CCG-2961 "Children with Untreated AML or MDS"
B973
Laboratory-Clinical Studies of Neuroblastoma
E-13
A Case Control Study of Hodgkin's Disease in Childhood
E-21
A Case Control Study of Primitive Neuroextodermal Tumor of Brain in Young Children
E-22
A Case Control Study of Malignant Germ Cell Tumors in Children
E-23
Epidemiology of Down Syndrome-Leukemia and Down Syndrome
P9485
Assesment of the Role of Minimal Access Surgery in the Treatment of Childhood Cancer: Intergroup Laparoscopy Protocol
R9701
Use of Thallium-201 Scintigraphy in Assessing Therapeutic Resonse of Pediatric Osteogenic Sarcoma to Chemotherapy (Companion Study to CCG-7921/7943)
S921
A Companion of Urokinase versus Heparin in Preventing Infection in Central Venous Devices in Children with Malignancies
COGUM-0791
Soft Tissue Sarcoma (Arndt)
COGUM-0192
Phase II Pre-Irradiation Chemotherapy for Central Nervous System Germ Cell Malignancies (Smithson)
COGUM-0292
Renal Function in OS Pilot II (Arndt)
COGUM-0692L
The Treatment of Localized Langerhans Cell Histiocytosis of Bone with Intralesional Infiltration of Corticosteroids (Nesbit)
COGUM-0295
Hemophagocytic Lymphohistiocytosis (Nesbit)
COGUM-0196
Single Versus Multiple Dosing Versus Continuous Infusion of Ondansetron in the Control of Chemotherapy Related Emesis (Matloub)
COGUM-0296
Antithymocyte Globulin Cyclosporine, and G-CSF for the treatment of Aplastic Anemia (Matloub)
COGUM-0197
Treatment of Severe Progressivbe Langerhans Cell Histiocytosis (LCH-11) Second International Study (Nesbit)
COGUM-8092
Intrathecal Chemotherapy for CNS Leukemia or Other Meningeal Tumors (Arndt) Patients must be treated at the Mayo Clinic