Hematology-Oncology Faculty
John Perentesis, MD
Associate Professor of Pediatrics
Current Position and Appointment
- Associate Professor of Pediatric Hematology and Oncology
- Director of Pediatric High-Risk Hematology & Oncology Program
University of Minnesota Cancer Center
- University of Minnesota Medical School - Attending Physician
Fairview - University Hospital, Minneapolis, MN
Education
- Premedical/Medical School: 1974 -1980:
The University of Michigan Integrated Premedical-Medical Program
- Pediatric Specialty Residency 1980 - 1983: The University of Minnesota, Department of Pediatrics
- Fellowship and Research Training:
1983 - 1984: American Cancer Society Clinical Fellowship
1983 - 1986: University of Minnesota Pediatric Hematology-Oncology-Bone Marrow
Transplantation Fellowship
1986 - 1990: University of Minnesota Department of Biochemistry & Pediatrics
NIH Physician-Scientist Postdoctoral Research Fellow:
Awards, Honors, and Special Activities:
- National Institutes of Health NIAID Physician Scientist Award
- University of Minnesota Pediatric Fellows Research Symposium Award: 1987
- External Grant Reviewer, Ohio State Comprehensive Cancer Center: 1989
Professional Positions
- 1990 - 1997: Assistant Professor of Pediatric Hematology & Oncology
University of Minnesota Medical School
- 1997 - present: Associate Professor of Pediatric Hematology & Oncology,
Director, Pediatric Oncology High Risk Malignancy Program,
University of Minnesota Medical School
Awards and Honors
- University Children's Foundation Faculty Scholar Award 1991
- University of Minnesota Pew Scholars Award Clinical Nominee 1991
- Pediatric Resident Teaching Recognition: 1993, 1994, 1995
Professional Board Certification & Licensure
- National Board of Medical Examiners Diplomate
- American Board of Pediatrics Diplomate
- American Board of Pediatrics Hematology & Oncology Subspecialty Board Diplomate
- State of Minnesota Board of Medical Examiners
Professional Society Memberships
- American Society for Biochemistry and Molecular Biology
- American Association for Cancer Research
- American Society for Hematology
- International Society for Experimental Hematology
- American Society for Clinical Oncology
- Northwest Pediatrics Society
Research Program Activities and Support - National Grants Awarded
Active National Awards with Extramural Review:
- National Institutes of Health R01 ES07819: "Environmental Exposures and ras Mutations in Acute Leukemia" (Robison)
Co-P.I.: John P. Perentesis, M.D. Effort: 15%
Total Support: $1,137,803 Duration: 4/96 - 3/99
- National Childhood Cancer Fund: "Glutathione-S-Transferase Genotypes in Childhood Acute Leukemia"
Co-P.I.: John P. Perentesis, M.D. Effort: 10%
Total Support: $1,137,803 Duration: 4/97 - 3/99
- National Institutes of Health U10 CA07306: “Children’s Cancer Group Multi-Institution Clinical Trials Group” (Bleyer) - University of Minnesota Subcontract
Investigator: John P. Perentesis, M.D. Effort: 15%
- National Institutes of Health: "Therapy-Related Leukemia: Clinical / Biological Predictors"
P.I.: S. M. Davies, M.D., Ph.D.
Co-I.: John P. Perentesis, M.D. Effort: 10%
Total Support: $ 1,207,287 Duration: 3/98 - 2/03
Previous National Awards with Extramural Review:
- National Institutes of Health R29 CA58536: "Genetic Engineering of Targeted Therapies for Myeloid Leukemia"
P.I.: John P. Perentesis, M.D. Effort: 75%
Total Support: $ 514,500 Duration: 3/93 - 3/98
- Leukemia Society of America: "Translational Models for Novel Recombinant Bio-chemotherapy Regimens for Myeloid Leukemia"
P.I.: John P. Perentesis, M.D.
Total Support: $ 216,000 Duration: 9/95 - 12/97
- National Institutes of Health K11 AI00793: "Molecular Study of Ribosomal Toxins and Applications in Oncology"
P.I.: John P. Perentesis, M.D. Duration: 10/87 - 9/92
Research Program Activities and Support - National Grants Pending Review
- National Institutes of Health Chemoprevention RFA: “Children’s Cancer Group: Chemoprevention in High Risk Pediatric Populations” (Bleyer)
Co-P.I.: John P. Perentesis, M.D. Effort: 25%
- National Institutes of Health: “Pilot Studies for the Chemoprevention of Down Syndrome Leukemia”
P.I.: John P. Perentesis, M.D. Effort: 20%
Clinical Research Protocol Chairmanships
Principal Investigator and Chair:
- (1) MT9713: University Of Minnesota Study Of Amifostine Chemoprotection In Autologous Stem Cell Transplantation for High Risk Pediatric Solid Tumors and Brain Tumors.
M.D. Anderson and New York University participating as secondary institutions
- (2) Molecular Epidemiology Of Down Syndrome/Leukemia And Congenital Abnormalities.
This prospective multi-institution national study will include the University of Minnesota, Fairview Health System, the Children’s Health Care-Minneapolis / St. Paul system, Abbott/Allina Health System, Mayo Clinic, University of Indiana, University of
Investigator and Local Chair:
- (1) MT9808: National Cancer Institute T96-0037 Pilot Study of Tumor-Specific Peptide Vaccination and IL-2 with or without Autologous T Cell Transplantation in Resurrent Pediatric Sarcomas. This protocol is developed in conjunction with the joint University of Minnesota-National Cancer Institute Pediatric Oncology monthly High Risk Hematology and Oncology Telemedicine Conference.
- (2) A Phase I/II Study Of The Cytokine Myelopoietin With Ifosfamide, Carboplatin And Etoposide Chemotherapy In High Risk Pediatric Sarcomas
- (3) A Phase I Dose Escalation Study of Intrathecal DepoCyt (encapsulated Ara-C) in Pediatric Patients with Advanced Meningeal Malignancies
- (4) Children’s Cancer Group portfolio of Phase I and Phase II chemotherapy studies
National Committee Assignments
- Children’s Cancer Group (Arcadia, California): Director, Molecular Epidemiology Laboratory
- Chairman of Study B955: “Environmental exposures and ras mutations in leukemia”
- Committee Member: Acute Myeloid Leukemia Strategy Group, New Agents Committee, Biology and Translational Research Program, and Young Investigators Committee
- Aidan O'Neill Foundation (Omaha, Nebraska) National Grant Reviewer.
Click here to return to the Peds Hem/Onc home page
Last updated 1/12/1999