|
Ernesto Resnik, Ph.D.
Assistant Professor - Department of Pediatrics
|
Education and Background
- Undergraduate: University of Buenos Aires, School of Sciences,
Chemistry 1988
- Graduate: Dept of Biochemistry, University of Minnesota - Ph.D.
Biochemistry, Molecular Biology & Biophysics- 1994
- Thesis Title: Regulation of transcription of the aceBAK
operon in E.Coli.
- Supervisor: Prof. David C. LaPorte
- Postdoctoral: Institute of Human Genetics, University of Minnesota,
Postdoctoral Associate. 1994-1998
- Supervisor: Prof. Christopher C. Wylie
Awards
- 1986-1987 University of Buenos Aires, Graduate Research Assistantship
(competitive grant).
- 1987-1988 National Council for Research in Science and Technology Fellowship
(CONICET, Argentina) (4 years fellowship).
- 1989 Honorary Mention, Biochemistry Faculty to the best score in Doctoral
Preliminary Examination, Biochemistry Graduate Class of 1989.
Publications
- Wylie, C and Resnik, E. (1998) Manipulating Gene Expression in Xenopus
Oocytes and Embryos. in Methods in Molecular Biology. Developmental
Biology Protocols. Vol II. Edited by Tuan R.S. and Lo C.W. (in preparation)
- Resnik, E. (1997) b-cateninone player, two games. Nature Genetics
16 (1) 9-11
- Resnik, E., Pan, B., Ramani,N., Freundlich, M. and LaPorte, D.C. (1996)
Integration Host Factor amplifies the induction of the aceBAK operon of
E. coli by relieving IclR repression. J. Bacteriol., 178 (9), 2715-2717.
- Breiter, D., Resnik, E. and Banaszak,L. (1994) Engineering the quarternary
structure of an enzyme: construction and analysis of a monomeric form of
malate dehydrogenase from Escherichia coli. Protein Science, 3,
2023-2032.
- Resnik, E. and LaPorte, D.C. (1991) Introduction of single-copy sequences
into the chromosome of Escherichia coli: application to gene and operon
fusions. Gene, 107, 19-25
- Chung,T., Resnik, E., Stueland, C. and LaPorte, D.C. (1993) Relative
expression of the products of the Glyoxylate bypass operon: contributions
of transcription and translation. J. Bacteriol., 175 (14), 4572-4575
- Bertran,G., Artz, E., Resnik, E. and Nahmod, V. (1991) Inhibition of
Interferon gamma production by peripheral blood mononuclear leukocytes
of patients with sarcoidosis. Chest, 101, 996-999
- Navone N.M, Frisardi, A.L., Resnik, E.R., Batlle, A. and Polo, C. (1988)
Porphyrin biosynthesis in human breast cancer, Preliminary mimetic in vitro
studies. Med. Sci. Res., 16, 61-62
- Polo,C., Frisardi,A., Resnik, E., Schoua,A. and Batlle, A. M. (1988)
Factors influencing fluorescence spectra of free porphyrins. Clinical
Chemistry, 34, 757
Teaching experience
- 1984 Undergraduate Teaching Assistant, Department of Chemistry, University
of Buenos Aires, Argentina
- 1985-1986 Undergraduate Teaching Assistant, Department of Biology,
University of Buenos Aires, Argentina
- 1989-1990 Teaching Assistant in Medical Biochemistry, University of
Minnesota, MN.
- 1996 Faculty staff, MBL Embryology Course, Marine Biological Laboratory,
Woods Hole, MA.
Current Areas of Research Interest
The main focus of my work is to elucidate the molecular basis of early
vertebrate lung development, with particular emphasis on the mechanisms
of trancriptional regulation and the identification of the genes involved
in cellular commitment to lung organogenesis. Since the studies in mice
and tissue culture have been hampered by the inaccessibilty of the embryonic
material, we make use of the Xenopus Laevis (south-african clawed
frog) embryo as a model, mainly because its large size and its external
development makes it extremely well suited for embryological and bichemical
manipulations.
- Molecular mechanism of Lung Development. and Organogenesis:
- Transcription regulation.
- Characterization of lung primordia.
- Identification of genes involved in primordia formation and lung organogenesis.
You can contact Dr. Resnik through the Pediatric Critical Care
office at (612) 626-2916, or by e-mail at:
ernesto@gene.med.umn.edu
Back to the U of
M Peds Pulmonary and Critical Care Home Page
This page created 11/23/97. Questions or comments regarding this page
should be sent to the webmaster